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Updated: May 7, 2026

A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
Spontaneous resolution of ophthalmologic symptoms following bilateral traumatic carotid cavernous fistulae
Briana C Gapsis1, Roshni U Ranjit, Sharad Malavade
1University of Central Florida College of Medicine, Orlando, Florida;
Abstract:
A 38-year-old woman developed bilateral carotid cavernous fistulae (CCF) following a motor vehicle collision. Her initial ophthalmologic findings included periorbital edema, palsies of the left oculomotor and abducens nerves, and residual dilated pupils. She subsequently developed significant optic disc edema and retinal vascular dilation bilaterally. Patients with similar injuries typically require neurosurgical or vascular intervention. In this case, the patient's signs resolved spontaneously by 21 months after onset, leaving no residual ocular deficits.
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