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Updated: May 7, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
2-(Benz-yloxy)iso-quinoline-1,3(2H,4H)-dione
Yoshinobu Ishikawa1, Soichiro Matsuo
1School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.
Abstract:
The title compound, C16H13NO3, exists in the keto form and the iso-quinoline system is essentially planar (mean deviation = 0.0424 Å). The dihedral angle between the aromatic rings is 4.2 (2)°. In the crystal, mol-ecules are linked via weak C-H⋯O hydrogen bonds and C-H⋯π inter-actions, forming a three-dimensional structure.
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