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Updated: May 7, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
N,N-Diethyl-4-[1-phenyl-3-(pyridin-2-yl)-4,5-di-hydro-1H-pyrazol-5-yl]aniline
Ying-Zhong Zhu1, Hui Wang, Ping-Ping Sun
1Department of Chemistry, Anhui University, Hefei 230039, People's Republic of China ; Key Laboratory of Functional Inorganic Materials Chemistry, Hefei 230039, People's Republic of China.
Abstract:
In the title mol-ecule, C24H26N4, the pyrazoline ring assumes an envelope conformation with the aniline-bearing C atom at the flap position. The benzene ring and the pyridine ring form with the pyrazoline ring dihedral angles of 4.53 (1) and 6.26 (1)°, respectively. In turn, the aniline group is nearly perpendicular to the pyrazoline ring [dihedral angle = 79.96 (1)°]. The ethyl groups of the di-ethyl-amine substituent are disordered over two sets of sites, with an occupancy ratio of 0.624 (8):0.376 (8).
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