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Updated: May 7, 2026

Elucidating the Metabolism of 2,4-Dibromophenol in Plants
Published on: February 10, 2023
2,4-Di-bromo-1,3-dihy-droxy-9H-xanthen-9-one
Shi-Wen Huang1, Zheng-Min Yang, Fu-Ping Huang
1Key Laboratory for the Chemistry & Molecular Engineering of Medicinal Resources, Ministry of Education of China, School of Chemistry & Chemical Engineering, Guangxi Normal University, Guilin, 541004, People's Republic of China ; Department of Pharmacy, Youjiang Medical University for Nationalities, Baise 533000, People's Republic of China.
Abstract:
The title compound, C13H6Br2O4, derived from xanthone, a fundamental structural framework of active ingredients in many medicinal plants, and was synthesized by bromination of 1,3-di-hydroxyxanthen-9-one with N-bromo-succinimide. The mol-ecular conformation is essentially planar, the dihedral angle between the benzene rings being 1.1 (4)°. This conformation is favorable for the formation of an intra-molecular O-H⋯O hydrogen bond between a hy-droxy group and the xanthone carbonyl group. In the crystal, mol-ecules are associated into chains along the b-axis direction via C=O⋯H-O hydrogen bonds involving the other hy-droxy group.
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