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Interaction of psychoactive drugs with the Mg+2 requiring ATPase associated with isolated synaptic vesicles
Research Communications in Chemical Pathology and Pharmacology
|August 1, 1975
Abstract:
A large series of CNS active drugs have been tested for their possible effect on the Mg+2 dependent ATPase associated with isolated synaptic vesicles. Antipsychotic agents and cocaine showed inhibition, of a non-competitive type. The implications of this finding for a synaptic theory of psychosis are discussed.