Related Experiment Video
Updated: May 7, 2026

07:43
A Simple Approach to Perform TEER Measurements Using a Self-Made Volt-Amperemeter with Programmable Output Frequency
Published on: October 5, 2019
21.9K
Simulation of a current source with a Cole-Cole load for multi-frequency electrical impedance tomography
Summary
This study simulated an improved Howland current source for Electrical Impedance Tomography. The THS4021 operational amplifier demonstrated superior performance, maintaining stable output current across a wide frequency range and load types.
Area of Science:
- Electrical Engineering
- Biomedical Engineering
- Instrumentation
Background:
- Accurate current sources are crucial for Electrical Impedance Tomography (EIT) systems.
- Existing current sources face limitations at higher frequencies and with complex resistive loads.
- The Howland current source is a common topology, but improvements are needed for robust EIT hardware.
Purpose of the Study:
- To simulate and evaluate an improved Howland current source for EIT applications.
- To compare the performance of two operational amplifiers (THS4021 and OPA843) within the improved current source.
- To assess the current source's stability and output impedance across a range of frequencies and with a Cole-Cole load model.
Main Methods:
- Simulation of an improved Howland current source circuit.
- Modeling of a Cole-Cole impedance for realistic biological tissue representation.
- Comparative performance analysis of THS4021 and OPA843 operational amplifiers from 1 kHz to 1 MHz.
- Evaluation of output impedance and current stability.
Main Results:
- The THS4021 operational amplifier outperformed the OPA843 in the simulated improved Howland current source.
- The THS4021-based current source achieved an output impedance of 20 MΩ at 1 kHz and >320 kΩ at 1 MHz.
- A constant and stable output current of up to 4 mA was maintained across the tested frequencies and with the Cole-Cole load.
Conclusions:
- The improved Howland current source utilizing the THS4021 offers enhanced performance for EIT systems.
- This configuration provides a stable current output suitable for various biological tissue impedances.
- The simulation results support the use of the THS4021 for developing more accurate and reliable EIT hardware.
More Related Videos
Related Concept Videos
Mesh Analysis with Current Sources
2.4K
Mesh analysis becomes simpler when analyzing circuits with current sources, whether independent or dependent. The presence of current sources reduces the number of equations required for analysis. Two cases illustrate this:
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
2.4K
Electron Microscope Tomography and Single-particle Reconstruction
2.1K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.1K
Computed Tomography
7.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
7.6K
Source Transformation for AC Circuits
1.2K
The process of source transformation in the frequency domain entails the conversion of a voltage source, positioned in series with an impedance, into a current source that is parallel to an impedance, or the other way around. It is essential to maintain the following relationships while transitioning from one source type to another.
1.2K
Induced Electric Fields: Applications
2.7K
An important distinction exists between the electric field induced by a changing magnetic field and the electrostatic field produced by a fixed charge distribution. Specifically, the induced electric field is nonconservative because it does not work in moving a charge over a closed path. In contrast, the electrostatic field is conservative and does no net work over a closed path. Hence, electric potential can be associated with the electrostatic field but not the induced field. The following...
2.7K
Bode Plots Construction
1.0K
The Bode plot is an essential tool in control system analysis, mapping the frequency response of a system through a magnitude plot and a phase plot, both against a logarithmic frequency axis. To construct a Bode plot, consider the transfer function H(ω):
1.0K

