Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of Blood Vessels01:07

Development of Blood Vessels

2.1K
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
2.1K
Mechanism of Angiogenesis01:10

Mechanism of Angiogenesis

6.4K
Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...
6.4K
Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

2.9K
Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
2.9K
Vascular Spasm01:16

Vascular Spasm

5.0K
The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
5.0K
Morphogenesis02:19

Morphogenesis

20.0K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
20.0K
Seedless Vascular Plants03:24

Seedless Vascular Plants

54.6K
Seedless Vascular Plants Were the First Tall Plants on Earth
54.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Local peptide signalling induces stomatal closure under drought stress.

Nature communications·2025
Same author

LL3, a homolog of LONESOME HIGHWAY, regulates vascular cell proliferation in the root apical meristem.

Plant & cell physiology·2025
Same author

A cytokinin response maximum induces and activates bifacial stem cells for radial growth.

Nature plants·2025
Same author

Shoot apex-derived CLE46 peptide signal spatiotemporally restricts root regeneration in Arabidopsis.

Plant & cell physiology·2025
Same author

Coordination and regulation of vascular development in roots.

Current opinion in plant biology·2025
Same author

Publisher Correction: A non-canonical BZR/BES transcription factor regulates the development of haploid reproductive organs in Marchantia polymorpha.

Nature plants·2024

Related Experiment Video

Updated: May 7, 2026

Visualization and Quantitative Analysis of Embryonic Angiogenesis in Xenopus tropicalis
06:05

Visualization and Quantitative Analysis of Embryonic Angiogenesis in Xenopus tropicalis

Published on: May 25, 2017

7.9K

Initiation of vascular development.

Kyoko Ohashi-Ito1, Hiroo Fukuda

  • 1Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-0033, Japan.

Physiologia Plantarum
|October 12, 2013
PubMed
Summary
This summary is machine-generated.

Vascular development in plants, crucial for growth, is initiated by auxin flow. Recent research highlights key factors regulating vascular initial cell establishment in embryos and roots.

More Related Videos

Whole-mount Immunohistochemical Analysis for Embryonic Limb Skin Vasculature: a Model System to Study Vascular Branching Morphogenesis in Embryo
09:53

Whole-mount Immunohistochemical Analysis for Embryonic Limb Skin Vasculature: a Model System to Study Vascular Branching Morphogenesis in Embryo

Published on: May 20, 2011

17.1K
A Method for Labeling Vasculature in Embryonic Mice
09:58

A Method for Labeling Vasculature in Embryonic Mice

Published on: October 7, 2011

15.4K

Related Experiment Videos

Last Updated: May 7, 2026

Visualization and Quantitative Analysis of Embryonic Angiogenesis in Xenopus tropicalis
06:05

Visualization and Quantitative Analysis of Embryonic Angiogenesis in Xenopus tropicalis

Published on: May 25, 2017

7.9K
Whole-mount Immunohistochemical Analysis for Embryonic Limb Skin Vasculature: a Model System to Study Vascular Branching Morphogenesis in Embryo
09:53

Whole-mount Immunohistochemical Analysis for Embryonic Limb Skin Vasculature: a Model System to Study Vascular Branching Morphogenesis in Embryo

Published on: May 20, 2011

17.1K
A Method for Labeling Vasculature in Embryonic Mice
09:58

A Method for Labeling Vasculature in Embryonic Mice

Published on: October 7, 2011

15.4K

Area of Science:

  • Plant biology
  • Developmental biology
  • Plant anatomy

Background:

  • Vascular development is essential for plant growth and occurs during embryogenesis and lateral organ formation.
  • Understanding the initiation of vascular development is a key goal in plant biology.
  • Auxin flow plays a critical role in initiating vascular development.

Purpose of the Study:

  • To review recent findings on the initiation of vascular development.
  • To discuss the key factors regulating vascular initial cell establishment.
  • To provide insights into the mechanisms underlying vascular development.

Main Methods:

  • Literature review of recent studies.
  • Synthesis of current knowledge on vascular development.
  • Analysis of key regulatory factors and auxin flow dynamics.

Main Results:

  • Recent studies have identified key factors involved in vascular initial cell establishment.
  • Auxin flow is confirmed as a crucial element in initiating vascular development.
  • The review consolidates understanding of molecular and cellular mechanisms.

Conclusions:

  • The initiation of vascular development is a complex process regulated by specific factors and auxin.
  • Further research is needed to fully elucidate the intricate mechanisms.
  • This review provides a comprehensive overview of the current state of knowledge.