Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microtubules in Signaling01:22

Microtubules in Signaling

1.5K
The primary cilium, made up of microtubules, acts as antennae on the cell surfaces for relaying external stimuli into the cells. These fine hair-like structures are present, generally one per cell. These are non-motile cilia in a 9+0 microtubules arrangement, where the central pair of microtubules are absent. The primary cilia arise from the basal body embedded in the cell membrane. Intraflagellar transport (IFT) carries requisite proteins from the cytoplasm to the cilium because the primary...
1.5K
Huntington Disease l: Introduction01:21

Huntington Disease l: Introduction

166
Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show...
166
Pedigree Analysis01:35

Pedigree Analysis

78.9K
Overview
78.9K
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

79
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
79
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

108
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
108
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

1.1K
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Joint Associations of Multidimensional Socioeconomic Status and Healthy Lifestyle with Prevalent Hypertension: A Large Population-Based Study in Northwest China.

Nutrients·2026
Same author

Discovery of YTB53, a Marine-Derived MNK-Active Anti-Acute Myeloid Leukemia Lead with Multi-Kinase Activity.

Journal of medicinal chemistry·2026
Same author

Global, regional, and national burden of type 1 diabetes mellitus in children and adolescents: trend and health inequality analyses based on multiple databases, 1990-2021.

Science bulletin·2026
Same author

Global Trends and Inequalities in Diabetes Prevalence and Treatment Coverage Among Adults Aged ≥ 45 Years, 1990-2040: Insights From the NCD-RisC Database.

Diabetes/metabolism research and reviews·2026
Same author

The impact of modifiable social determinants on tuberculosis incidence: insights from a Bayesian spatiotemporal and counterfactual analysis.

BMC public health·2026

Related Experiment Video

Updated: May 7, 2026

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

8.2K

Kikuchi disease in Connecticut.

Henry M Feder1, Jinli Liu2, William N Rezuke2

  • 1Departments of Family Medicine and Pediatrics, University of Connecticut Health Center, Farmington, CT.

The Journal of Pediatrics
|October 12, 2013
PubMed
Summary

Kikuchi disease, a rare condition causing swollen lymph nodes and fever, can mimic cancer. This report details three new US cases, adding to the limited understanding of this disorder in the United States.

Keywords:
ANAAnti-LA antibodyAnti-RO antibodyAntinuclear antibodiesCCMCCMVConnecticut Children's Medical CenterCytomegalovirusEBVESREpstein-Barr virusErythrocyte sedimentation rateLALDHLactate dehydrogenasePPDPurified protein derivativeROSLESMSystemic lupus erythematosusWBCWhite blood cell countanti-Smith antibody

More Related Videos

Tricolor Transgenic Murine Model for Studying Growth Plate Injury
07:58

Tricolor Transgenic Murine Model for Studying Growth Plate Injury

Published on: September 6, 2024

1.4K
Quantitative Fluorescence In Situ Hybridization FISH and Immunofluorescence IF of Specific Gene Products in KSHV-Infected Cells
06:21

Quantitative Fluorescence In Situ Hybridization FISH and Immunofluorescence IF of Specific Gene Products in KSHV-Infected Cells

Published on: August 27, 2019

12.0K

Related Experiment Videos

Last Updated: May 7, 2026

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

8.2K
Tricolor Transgenic Murine Model for Studying Growth Plate Injury
07:58

Tricolor Transgenic Murine Model for Studying Growth Plate Injury

Published on: September 6, 2024

1.4K
Quantitative Fluorescence In Situ Hybridization FISH and Immunofluorescence IF of Specific Gene Products in KSHV-Infected Cells
06:21

Quantitative Fluorescence In Situ Hybridization FISH and Immunofluorescence IF of Specific Gene Products in KSHV-Infected Cells

Published on: August 27, 2019

12.0K

Area of Science:

  • Pathology
  • Immunology
  • Oncology

Background:

  • Kikuchi disease is a rare, benign lymphadenopathy of unknown cause.
  • It presents with fever, weight loss, and painful lymph node swelling.
  • Differential diagnosis includes lymphoma and other malignant conditions.

Observation:

  • This study reports three new cases of Kikuchi disease in the United States.
  • It also reviews previously documented cases within the US.
  • The disease is known to be endemic in Asia.

Findings:

  • Diagnosis of Kikuchi disease is confirmed through lymph node biopsy.
  • The condition is self-limiting, resolving without specific treatment.
  • Increased recognition of Kikuchi disease in the US is noted.

Implications:

  • Highlights the importance of considering Kikuchi disease in the differential diagnosis of lymphadenopathy, especially in the US.
  • Contributes to a better understanding of its geographic distribution and clinical presentation.
  • Aids clinicians in avoiding misdiagnosis and unnecessary aggressive treatments.