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Brain Imaging

Brain Imaging

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Related Experiment Video

Updated: May 7, 2026

Combined Invasive Subcortical and Non-invasive Surface Neurophysiological Recordings for the Assessment of Cognitive and Emotional Functions in Humans

Combined Invasive Subcortical and Non-invasive Surface Neurophysiological Recordings for the Assessment of Cognitive and Emotional Functions in Humans

Published on: May 19, 2016

Deep brain stimulation for cognitive disorders.

Adrian W Laxton¹, Nir Lipsman, Andres M Lozano

¹Department of Neurosurgery, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.

Handbook of Clinical Neurology

|October 12, 2013

Summary

This summary is machine-generated.

Deep brain stimulation (DBS) shows promise for treating cognitive disorders like Alzheimer's disease (AD) and dementia. Research reviews DBS targets for modulating brain circuitry in dementia patients.

Keywords:

Alzheimer's disease deep brain stimulation dementia fornix memory neuromodulation nucleus basalis of Meynert

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Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus

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Published on: March 8, 2015

Area of Science:

Neuroscience
Neurology
Cognitive Science

Background:

Cognitive disorders, including dementia and Alzheimer's disease (AD), represent a significant and growing societal burden.
Existing treatments for dementia and AD are limited in their ability to halt or slow disease progression.
Deep brain stimulation (DBS) offers a novel therapeutic approach by targeting specific brain circuits involved in memory and cognition.

Purpose of the Study:

To review the current literature on the use of deep brain stimulation (DBS) for Alzheimer's disease (AD) and Parkinson's disease dementia.
To identify promising neuroanatomical targets for DBS in modulating pathological brain activity associated with cognitive decline.

Main Methods:

Literature review of studies investigating deep brain stimulation (DBS) in the context of dementia and Alzheimer's disease (AD).
Analysis of neuroanatomical targets and their effects on cognitive and memory networks.

Main Results:

Deep brain stimulation (DBS) has demonstrated potential in affecting memory and cognitive networks.
Specific neuroanatomical targets show promise for modulating underlying pathological activity in brain circuitry relevant to dementia.

Conclusions:

Deep brain stimulation (DBS) presents a potentially promising avenue for developing novel treatments for dementia and Alzheimer's disease (AD).
Further research into specific neuroanatomical targets is warranted to optimize DBS therapy for cognitive disorders.