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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Updated: May 7, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Brain stimulation in migraine.

Filippo Brighina¹, Giuseppe Cosentino, Brigida Fierro

¹Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Palermo, Italy.

Handbook of Clinical Neurology

|October 12, 2013

Summary

This summary is machine-generated.

Noninvasive brain stimulation techniques like transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) offer promising avenues for understanding and treating migraine. These methods modulate cortical excitability, paving the way for novel therapeutic strategies.

Keywords:

TMS aura cortical excitability homeostatic plasticity migraine noninvasive brain stimulation rTMS tDCS

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Area of Science:

Neuroscience
Neurology
Medical Technology

Background:

Migraine is a widespread neurological disorder causing significant disability and socioeconomic impact.
The precise etiopathogenesis of migraine remains incompletely understood, with growing interest in cortical excitability.
Dysfunctional cortical excitability is hypothesized to play a role in migraine pathophysiology.

Purpose of the Study:

To critically review the role of noninvasive brain stimulation (NIBS) in migraine pathophysiology.
To evaluate NIBS techniques as potential therapeutic approaches for migraine treatment.
To discuss the advantages, limitations, and future applications of NIBS in migraine management.

Main Methods:

Utilized transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) to investigate cortical excitability, activation, and plasticity in migraine.
Explored the capacity of repetitive TMS (rTMS) and tDCS to modulate cortical activity and induce persistent effects.
Reviewed existing evidence on the application of NIBS in both symptomatic and preventive treatment of migraine.

Main Results:

TMS and tDCS have demonstrated safety and efficacy in exploring cortical excitability and plasticity in migraine patients.
NIBS techniques show potential for modulating cortical activity, suggesting therapeutic applications.
These methods offer a novel perspective for noninvasive neurostimulation in headache treatment.

Conclusions:

Noninvasive brain stimulation techniques are valuable tools for elucidating migraine pathophysiology.
TMS and tDCS represent promising therapeutic strategies for migraine, with potential for symptomatic and preventive treatment.
Further research and development are needed to optimize NIBS applications in clinical practice.