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[Fibrin pleurodesis in malignant pleural effusions]
Deutsche Medizinische Wochenschrift (1946)
|September 6, 1985
Summary
Fibrin pleurodesis effectively treated malignant pleural effusions in 30 patients. This procedure demonstrated a high success rate with minimal side effects, offering a promising therapeutic option.
Area of Science:
- Thoracic Surgery
- Oncology
- Biochemistry
Context:
- Malignant pleural effusions present a significant challenge in patient care.
- Effective management of malignant pleural effusions is crucial for improving patient quality of life.
Purpose:
- To evaluate the efficacy and safety of fibrin pleurodesis for managing malignant pleural effusions.
- To assess the role of aprotinin in inhibiting local fibrinolysis during the procedure.
Summary:
- Fibrin pleurodesis was performed on 30 patients with malignant pleural effusions using a pleural catheter and intrapleural instillation of aprotinin, fibrinogen, and thrombin.
- Complete success was achieved in 19 out of 27 evaluable patients, with partial success in two.
- The procedure exhibited a low incidence of side effects, with only three patients experiencing subfebrile temperature.
Impact:
- Fibrin pleurodesis is presented as an effective treatment for malignant pleural effusions.
- The study highlights the procedure's favorable safety profile, with only a 10% side effect rate.
- This minimally invasive approach offers a viable alternative for palliative care in oncology patients.