Related Experiment Video
Updated: May 7, 2026
05:39
Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
2.8K
Non-invasive ventilation after surgery in amyotrophic lateral sclerosis
C Olivieri1, C A Castioni, S Livigni
1Anesthesia and Intensive Care, Maggiore della Carità University Hospital, Novara, Italy.
Acta Neurologica Scandinavica
|October 15, 2013
Summary
Non-invasive ventilation (NIV) safely prevents post-operative pulmonary complications in amyotrophic lateral sclerosis (ALS) patients undergoing stem cell transplantation. This strategy supports stable breathing after surgery, even in advanced disease stages.
Area of Science:
- Neurology
- Pulmonology
- Anesthesiology
Background:
- Surgery in amyotrophic lateral sclerosis (ALS) patients poses anesthetic risks, particularly post-operative pulmonary complications (PPCs).
- Effective management of respiratory function is critical for this patient population.
Purpose of the Study:
- To evaluate the safety and efficacy of non-invasive ventilation (NIV) in preventing PPCs.
- To assess NIV's role in ALS patients undergoing stem cell transplantation.
Main Methods:
- Nine ALS patients received autologous mesenchymal stem cells via spinal cord surgery.
- Anesthesia involved propofol, remifentanil, and sevoflurane without muscle relaxants.
- Post-extubation, patients received NIV (positive and continuous positive pressure ventilation).
Main Results:
- Patients used NIV for an average of 3 hours and 12 minutes post-surgery.
- All patients achieved stable spontaneous breathing after NIV discontinuation.
- No respiratory failure occurred until the following day.
Conclusions:
- NIV is a safe strategy for preventing PPCs in ALS patients post-surgery.
- The chosen perioperative protocol is safe, even for patients with advanced ALS.
- NIV facilitates recovery and reduces respiratory complications in this high-risk group.
Related Concept Videos
01:23Mechanical Ventilation III: Noninvasive Ventilation
940
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
Noninvasive Positive-Pressure Ventilation...
940
01:23Mechanical Ventilation II: Invasive Ventilation
1.3K
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
1.3K
01:14Ventilatory Modes
2.3K
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
2.3K
01:22Cardiopulmonary Resuscitation II: ACLS Airway Management
1.2K
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
1.2K
01:29Mechanical Ventilation I: Indication and Settings
4.2K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
4.2K
01:30Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
964
Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
964