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Updated: May 7, 2026
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
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Psoriasis and smoking: a systematic review and meta-analysis
A W Armstrong1, C T Harskamp, J S Dhillon
1Department of Dermatology, University of California, Davis, 3301 C Street, Suite 1400, Sacramento, CA, 95816, U.S.A.
The British Journal of Dermatology
|October 15, 2013
Summary
Smoking is linked to a higher risk of developing psoriasis and is more prevalent in patients with the condition. This systematic review confirms smoking as an independent risk factor for psoriasis incidence.
Area of Science:
- Dermatology and Public Health
Background:
- Psoriasis is an inflammatory skin condition linked to cardiovascular issues.
- Patients with psoriasis show higher rates of active smoking.
- Smoking may contribute to psoriasis development.
Purpose of the Study:
- To systematically review and meta-analyze smoking prevalence in psoriasis patients.
- To assess smoking's contribution to psoriasis incidence.
Main Methods:
- Systematic review and meta-analysis of 25 prevalence and 3 incidence studies.
- Included 146,934 psoriasis patients and 529,111 controls for prevalence.
- Analyzed current and former smoking associations and dose-response effects.
Main Results:
- Significant association between psoriasis and current smoking (OR 1.78, CI 1.52-2.06).
- Significant association between psoriasis and former smoking (OR 1.62, CI 1.33-1.99).
- Incidence studies indicated smoking as a risk factor for psoriasis development.
Conclusions:
- Smoking is an independent risk factor for psoriasis development.
- Psoriasis patients exhibit higher smoking rates compared to non-patients.
- Findings highlight the importance of smoking cessation in psoriasis management.
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