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Pathogen inactivation and removal methods for plasma-derived clotting factor concentrates

Robert Klamroth1, Albrecht Gröner, Toby L Simon

  • 1Center for Vascular Medicine, Vivantes Klinikum im Friedrichshain, Berlin, Germany.

Transfusion
|October 15, 2013
PubMed
Summary

Ensuring pathogen safety in plasma-derived clotting factors involves rigorous donor screening, donation testing, and integrated viral inactivation/removal manufacturing steps. These measures are vital for preventing infectious agent transmission in patients with bleeding disorders.

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