Risk factors for acute kidney injury in patients undergoing same admission coronary angiography and valve replacement

Yijie Hu1, Zhiping Li, Jianming Chen

  • 1Department of Cardiovascular Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Yuzhong District, Chongqing, China.

Insights

Diabetes and cerebrovascular disease significantly increase the risk of acute kidney injury (AKI) in patients undergoing same-admission coronary angiography and valve replacement. Caution is advised for these high-risk individuals.

Area of Science:

  • Cardiology
  • Nephrology
  • Cardiovascular Surgery

Background:

  • Investigated risk factors for acute kidney injury (AKI) in patients undergoing same-admission coronary angiography (CAG) and valve replacement.
  • Examined a cohort of 283 patients undergoing valve surgery, with 71 included for analysis of preoperative CAG.
  • Focused on the incidence and predictors of AKI in a specific surgical population.

Purpose of the Study:

  • To identify risk factors for acute kidney injury (AKI) in patients undergoing combined coronary angiography and valve replacement.
  • To determine the association between pre-existing conditions and AKI development post-procedure.
  • To inform clinical practice regarding patient selection and procedural caution.

Main Methods:

  • Univariable and multivariate logistic regression analyses were employed.
  • Identified predictors of AKI using variables with p < 0.1 from univariable analysis and known AKI risk factors.
  • Included 71 patients undergoing same-admission coronary angiography and valve replacement.

Main Results:

  • Twenty-two (31.0%) patients developed AKI.
  • Diabetes mellitus (OR 10.361) and cerebrovascular disease (OR 26.070) were identified as significant independent risk factors for AKI.
  • Concomitant tricuspid valve repair/replacement and atrial fibrillation were risk factors in univariable analysis, but not significant in multivariate analysis.

Conclusions:

  • Diabetes mellitus and cerebrovascular disease are significant risk factors for AKI in patients undergoing same-admission CAG and valve replacement.
  • These procedures should be approached with caution in patients with diabetes and cerebrovascular disease.
  • Further research may explore preventative strategies for AKI in this vulnerable patient group.
Abstract

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