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Dip1 defines a class of Arp2/3 complex activators that function without preformed actin filaments

Andrew R Wagner1, Qing Luan, Su-Ling Liu

  • 1Institute of Molecular Biology and Department of Chemistry and Biochemistry, University of Oregon, Eugene, OR 97403, USA.

Current Biology : CB
|October 15, 2013
PubMed
Summary

Dip1 protein activates the Arp2/3 complex without needing existing filaments, initiating linear actin networks. This discovery reveals a novel mechanism for branched actin assembly, distinct from known pathways.

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