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CD46: the 'multitasker' of complement proteins

Hidekazu Yamamoto1, Antonella Francesca Fara, Prokar Dasgupta

  • 1Division of Transplant Immunology and Mucosal Biology, MRC Centre for Transplantation, King's College London, Guy's Hospital, London SE1 9RT, UK; The Urology Centre, Guy's and St. Thomas' NHS Foundations Trust, London SE1 9RT, UK.

The International Journal of Biochemistry & Cell Biology
|October 15, 2013
PubMed

Keywords:
(CBF1/Su(H)/Lag-1) transcription factor complexADAMAMDAP-1AutoimmunityB-cell lymphoma 2Bcl-2CCLCCPCD46CD46 cytoplasmic domain 1 or 2CSLCYT-1 or CYT-2ComplementDCDLG4DLLERK1/2FLT3FLT3LFMS-related tyrosine kinase 3FMS-related tyrosine kinase 3 ligandG protein-coupled receptorG protein-coupled receptor kinaseGASGATA3GOPCGPCRGRKGSK3βGTPGroup A Streptococcus pyogenesICER/CREMIFNILIPEXISInfectionJAKJNKJanus kinaseLATLDL receptor-related proteinLEFLRPLckMAPKMHCMMPMSMTOCNF-κBNICDNONotch intracellular domainPGE2RARCASLESNPSP-1SPAKSTATSTP regionSte20/SPS-1-related kinaseT cell receptorT helper cell/responseT-betT-box transcription factor TBX21T-cell factor/lymphocyte-enhancer-binding factorTCRTERTLRThTh1 cellsToll-like receptorUTa disintegrin and metalloproteinaseaHUSactivator protein 1age-related macular degenerationatypical hemolytic uremic syndromec-Jun amino-terminal kinasechemokine (C-C motif) ligandcomplement control protein domaindelta-like liganddendritic cellextracellular signal-regulated protein kinases 1 and 2glycogen synthase kinase 3βgolgi-associated PDZ and coiled-coil motif-containing proteinguanine triphosphatehuman homologue of Discs Large (DLG) Drosophilaimmune dysregulation, polyendocrinopathy, enteropathy, X-linked-likeimmunological synapseinducible cAMP early repressor/cAMP response element modulatorinterferoninterleukinlinker for activation of T cellslymphocyte-specific protein tyrosine kinasemajor histocompatibility complexmatrix metalloproteinasemicrotubule organizing centremitogen-activated protein kinasemultiple sclerosisnTregnatural regulatory T cellnitric oxidenuclear factor kappa-light-chain-enhancer of activated B cellsprostaglandin E2regulators of complement activityrheumatoid arthritisserine, threonine, proline-rich regionsignal transducer and activator of transcriptionsingle-nucleotide polymorphismspecificity protein 1systemic lupus erythematosustrans-acting T-cell-specific transcription factor GATA3transepithelial resistanceuntranslated region

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