Related Experiment Video

Updated: May 7, 2026

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

17.8K

Nanotechnology approaches for personalized treatment of multidrug resistant cancers

Tamara Minko1, Lorna Rodriguez-Rodriguez, Vitaly Pozharov

  • 1Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, NJ 08854, USA; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.

Advanced Drug Delivery Reviews
|October 15, 2013
PubMed

Keywords:
ABCASOAntibodyAntisense oligonucleotidesCD44CPTCancer stem cellsDBDDDSDOXDrug delivery systemEPRIC(50) doseLHRHNBDNLCPAMAMPassive and active targetingPeptidesPump and nonpump resistanceSNPTMDTPADDSa dose that kills 50% of cellsadenosine triphosphate (ATP)-binding cassetteantisense oligonucleotidescamptothecindoxorubicindrug delivery systemdrug-binding domainenhanced permeability and retention effectluteinizing hormone-release hormonenanostructured lipid carriersnucleotide-binding domainpoly(amido amine)siRNAsingle-nucleotide polymorphismsmall interfering RNAtargeted proapoptotic drug delivery systemtransmembrane domain

More Related Videos

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms08:46

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms

Published on: December 9, 2015

12.8K
Automating Tumor Implantation in Zebrafish Larvae for Cancer Research and Medicine06:14

Automating Tumor Implantation in Zebrafish Larvae for Cancer Research and Medicine

Published on: September 19, 2025

1.2K

Related Concept Videos

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.0K
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

1.5K
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

1.1K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

1.5K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.1K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
2.7K