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Updated: May 7, 2026

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Cardiac rehabilitation and outcome in stable outpatients with recent myocardial infarction
Roser Coll-Fernández1, Ramon Coll2, Teresa Pascual3
1Department of Physical Medicine and Rehabilitation, Parc Taulí Sabadell, Hospital Universitari, Sabadell, Barcelona, Spain.
Insights
Cardiac rehabilitation significantly reduces mortality rates in patients following a recent myocardial infarction (MI). This structured program also shows a trend towards lowering subsequent ischemic events, improving patient outcomes.
Area of Science:
- Cardiology
- Public Health
- Rehabilitation Medicine
Background:
- Recent myocardial infarction (MI) poses a significant risk for mortality and subsequent ischemic events.
- Cardiac rehabilitation is a structured program designed to improve cardiovascular health and recovery post-MI.
Purpose of the Study:
- To compare mortality and subsequent ischemic event rates in patients with recent MI based on participation in cardiac rehabilitation versus no rehabilitation.
- To determine the independent association of cardiac rehabilitation with patient outcomes after MI.
Main Methods:
- A longitudinal observational study involving 1043 patients with recent acute MI.
- Data collected from an ongoing registry of outpatients, with 521 participants (50%) engaging in cardiac rehabilitation.
- Subsequent ischemic events (MI, ischemic stroke, limb amputation) and mortality rates were tracked over an 18-month follow-up period.
Main Results:
- Patients in cardiac rehabilitation experienced significantly lower mortality rates (0.16 vs 5.57 deaths per 100 patient-years) and a trend towards fewer subsequent ischemic events (1.65 vs 4.54 events per 100 patient-years).
- Multivariate analysis confirmed cardiac rehabilitation was independently associated with a significantly lower risk of death (HR=0.08, P=.016).
- A nonsignificant reduction in subsequent ischemic events was observed in the cardiac rehabilitation group (HR=0.65).
Conclusions:
- Cardiac rehabilitation is independently associated with a significant reduction in mortality for patients recovering from a recent MI.
- While not statistically significant in this study, cardiac rehabilitation demonstrated a trend towards decreasing subsequent ischemic events.
Objective:
To compare the mortality rate and the rate of subsequent ischemic events (myocardial infarction [MI], ischemic stroke, or limb amputation) in patients with recent MI according to the use of cardiac rehabilitation or no rehabilitation.
Design:
Longitudinal observational study.
Setting:
Ongoing registry of outpatients.
Participants:
Patients (N=1043) with recent acute MI were recruited; of these, 521 (50%) participated in cardiac rehabilitation.
Interventions:
Not applicable.
Main Outcome Measures:
Subsequent ischemic events and mortality rates were registered.
Results:
Over a mean follow-up of 18 months, 50 patients (4.8%) died and 49 (4.7%) developed 52 subsequent ischemic events (MI: n=43, ischemic stroke: n=6, limb amputation: n=3). Both the mortality rate (.16 vs 5.57 deaths per 100 patient-years; rate ratio=.03; 95% confidence interval [CI], 0.0-0.1]) and the rate of subsequent ischemic events (1.65 vs 4.54 events per 100 patient-years; rate ratio=0.4; 95% CI, 0.2-0.7) were significantly lower in cardiac rehabilitation participants than in nonparticipants. Multivariate analysis confirmed that patients in cardiac rehabilitation had a significantly lower risk of death (hazard ratio=.08; 95% CI, .01-.63; P=.016) and a nonsignificant lower risk of subsequent ischemic events (hazard ratio=.65; 95% CI, .30-1.42).
Conclusions:
The use of cardiac rehabilitation in patients with recent MI was independently associated with a significant decrease in the mortality rate and a nonsignificant decrease in the rate of subsequent ischemic events.
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