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Updated: May 7, 2026

An Aquatic Microbial Metaproteomics Workflow: From Cells to Tryptic Peptides Suitable for Tandem Mass Spectrometry-based Analysis
Published on: September 15, 2015
Microbial diversity associated with tetrodotoxin production in marine organisms
V Pratheepa1, Vitor Vasconcelos
1CIIMAR, Marine and Environmental Research Center, Porto University, Rua dos Bragas, 289, 4050-123 Porto, Portugal.
Abstract:
Tetrodotoxin (TTX), is a potent neurotoxin found in genetically diversed organisms. Many TTX producing microorganism have also been isolated from TTX bearing animals. The TTX producing microbes found in four different phylum (Proteobacteria, Actinobacteria, Firmicutes and Bacteroidetes), the Proteobacteria are the dominating one. In most of the cases, TTX producing microbes are found in the intestine of the TTX producing vector indicating the origin of TTX through food chain. This paper reviews the TTX and its analogs and the geographic distribution of TTX in symbiotic microorganism and its production.
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