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Updated: May 7, 2026

Author Spotlight: Functionalizing Metal-Organic Frameworks: Advancements, Challenges, and the Power of Post-Synthetic Ligand Exchange
Published on: June 23, 2023
The interaction of molybdenum pentachloride with O- and S-heterocycles
Lucilla Favero1, Fabio Marchetti, Guido Pampaloni
1University of Pisa, Dipartimento di Scienze Farmaceutiche (Sezione Chimica Bioorganica), Via Bonanno 33, I-56126 Pisa, Italy.
Abstract:
The 1 : 2 molar reactions of MoCl5, in dichloromethane at room temperature, with tetrahydrofuran (thf), tetrahydropyran (thp), dioxane and tetrahydrothiophene (tht) afforded, respectively, [Mo(O)Cl3(thf)]2, 1, and MoCl4(L)2 (L = thp, 2; dioxane, 3; tht, 4), in 81-87% yields. The molecular structures of 1, 2 and 4 were ascertained by X-ray diffractometry. DFT and spectroscopic (IR, NMR) studies were carried out in order to shed light on thermodynamic and kinetic aspects of the reaction pathways.
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