Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coordination of Gene Expression Processes in Bacteria01:29

Coordination of Gene Expression Processes in Bacteria

1.1K
The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
1.1K
Plasticity00:58

Plasticity

2.2K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
2.2K
Stringent Response in E. coli01:23

Stringent Response in E. coli

533
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
533
Other Stress Responses in Bacteria01:30

Other Stress Responses in Bacteria

593
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
593
Chemotaxis in E. coli01:27

Chemotaxis in E. coli

1.4K
Chemotaxis in Escherichia coli is a sensory-driven motility mechanism that enables bacteria to navigate chemical gradients, moving toward beneficial environments while avoiding harmful conditions. This process relies on a signal transduction system integrating external chemical cues with flagellar motor control.Chemoreceptors and Signal DetectionE. coli detects chemical gradients through methyl-accepting chemotaxis proteins (MCPs), which are membrane-bound chemoreceptors that sense attractants...
1.4K
Bacterial Signaling01:30

Bacterial Signaling

29.9K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
29.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization and treatment patterns of patients treated with immediate-release sodium oxybate for narcolepsy: A propensity score-matched cohort study.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2025
Same author

Demographic characteristics and comorbidities of patients with narcolepsy: a propensity-matched cohort study.

Sleep advances : a journal of the Sleep Research Society·2024
Same author

South-East Asian strains of <i>Plasmodium falciparum</i> display higher ratio of non-synonymous to synonymous polymorphisms compared to African strains.

F1000Research·2016
Same author

Structural mapping of Kelch13 mutations associated with artemisinin resistance in malaria.

Journal of structural and functional genomics·2016
Same author

Association between intrinsic disorder and serine/threonine phosphorylation in Mycobacterium tuberculosis.

PeerJ·2015
Same author

Bacterial evolution of antibiotic hypersensitivity.

Molecular systems biology·2013

Related Experiment Video

Updated: May 7, 2026

Continuous Measurement of Biological Noise in Escherichia Coli Using Time-lapse Microscopy
08:25

Continuous Measurement of Biological Noise in Escherichia Coli Using Time-lapse Microscopy

Published on: April 27, 2021

3.3K

Coupling between noise and plasticity in E. coli.

Gajinder Pal Singh1

  • 1School of Biotechnology, KIIT University, Bhubaneswar 751024, Odisha, India.

G3 (Bethesda, Md.)
|October 15, 2013
PubMed
Summary

Gene expression variability, known as noise and plasticity, positively correlates in E. coli, similar to yeast. This coupling is influenced by gene characteristics and regulation, suggesting a conserved biological mechanism.

Keywords:
expression plasticityexpression responsivenessgene expression noisegene expression regulation

More Related Videos

Sealable Femtoliter Chamber Arrays for Cell-free Biology
13:44

Sealable Femtoliter Chamber Arrays for Cell-free Biology

Published on: March 11, 2015

9.5K
Method for Labeling Transcripts in Individual Escherichia coli Cells for Single-molecule Fluorescence In Situ Hybridization Experiments
07:51

Method for Labeling Transcripts in Individual Escherichia coli Cells for Single-molecule Fluorescence In Situ Hybridization Experiments

Published on: December 21, 2017

7.8K

Related Experiment Videos

Last Updated: May 7, 2026

Continuous Measurement of Biological Noise in Escherichia Coli Using Time-lapse Microscopy
08:25

Continuous Measurement of Biological Noise in Escherichia Coli Using Time-lapse Microscopy

Published on: April 27, 2021

3.3K
Sealable Femtoliter Chamber Arrays for Cell-free Biology
13:44

Sealable Femtoliter Chamber Arrays for Cell-free Biology

Published on: March 11, 2015

9.5K
Method for Labeling Transcripts in Individual Escherichia coli Cells for Single-molecule Fluorescence In Situ Hybridization Experiments
07:51

Method for Labeling Transcripts in Individual Escherichia coli Cells for Single-molecule Fluorescence In Situ Hybridization Experiments

Published on: December 21, 2017

7.8K

Area of Science:

  • * Molecular Biology
  • * Genomics
  • * Evolutionary Biology

Background:

  • * Gene expression exhibits variability due to environmental changes (plasticity) and random fluctuations within identical cells (noise).
  • * In yeast, noise and plasticity are positively correlated, influenced by promoter architecture and gene essentiality.
  • * Understanding this coupling in prokaryotes like E. coli, with different regulatory mechanisms, is crucial.

Purpose of the Study:

  • * To investigate the correlation between gene expression noise and plasticity in Escherichia coli.
  • * To identify factors influencing this noise-plasticity coupling in a prokaryotic system.
  • * To compare the findings in E. coli with those in yeast to infer conserved mechanisms.

Main Methods:

  • * Analysis of genome-wide data on gene expression noise and plasticity in E. coli.
  • * Statistical examination of the correlation between noise and plasticity.
  • * Investigation of the influence of gene expression levels, essentiality, dosage sensitivity, and regulatory elements on the coupling.

Main Results:

  • * A significant positive correlation between gene expression noise and plasticity was observed in E. coli.
  • * The coupling strength was influenced by gene expression level, essentiality, dosage sensitivity, and regulation by specific proteins and factors.
  • * Key influencing factors in E. coli showed parallels with those identified in yeast.

Conclusions:

  • * Noise-plasticity coupling is a conserved phenomenon across evolutionarily distant organisms like yeast and E. coli.
  • * The mechanism underlying noise-plasticity coupling may be similar in both prokaryotes and eukaryotes.
  • * This conserved coupling suggests it is an important, potentially evolvable, trait with implications for gene expression regulation.