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Updated: May 7, 2026
Orthotopic Implantation of Patient-Derived Cancer Cells in Mice Recapitulates Advanced Colorectal Cancer
Published on: February 10, 2023
Intraperitoneal chemotherapy (IPC) for peritoneal carcinomatosis: review of animal models
Félix Gremonprez1, Wouter Willaert, Wim Ceelen
1Department of Surgery, Ghent University Hospital, Ghent, Belgium.
Abstract:
The development of suitable animal models is essential to experimental research on intraperitoneal chemotherapy (IPC). This review of the English literature (MEDLINE) presents a detailed analysis of current animal models and gives recommendations for future experimental research. Special consideration should be given to cytotoxic drug dose and concentration, tumor models, and outcome parameters.
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