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Updated: May 7, 2026
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
Published on: June 7, 2015
Early-stage central lung cancer and volumetric modulated arc therapy: a dosimetric case study with literature review
Vladimir Valakh1, Philip Chan, Karen D'Adamo
1Department of Radiation Oncology, Temple University Hospital, Philadelphia, PA, U.S.A. vladimir.valakh@tuhs.temple.edu.
Background/Aim:
In the present article we review on the use of Volumetric Modulated Arc Therapy (VMAT) for a small lung nodule that was centrally located in close proximity to the mediastinal structures.
Case Report:
An inoperable patient with central, clinical stage IA adenocarcinoma of the right lung was treated with external-beam radiation therapy of 52.5 Gy in 15 factions. A single 360° coplanar arc VMAT plan (360-VMAT) was used for treatment and compared to step-and-shoot Intensity Modulation Radiotherapy (IMRT) and a single 180° ipsilateral partial arc VMAT plan (180-VMAT).
Results:
Planning Target Volume (PTV) coverage was not different, and 360-VMAT had the highest dose homogeneity. Both 360-VMAT and 180-VMAT reduced esophageal dose compared to IMRT. While IMRT had the lowest lung dose, all 3 plans achieved acceptable sparing of the lung. 180-VMAT had the highest dose conformity. Both 360-VMAT and 180-VMAT improved esophageal sparing compared to IMRT.
Conclusion:
Use of VMAT in early-stage, centrally located NSCLC is a promising treatment approach and merits additional investigation.
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