Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improving colorectal polyp size classification with virtual scale endoscopy: implications for resection strategy and surveillance.

Gastrointestinal endoscopy·2026
Same author

Missing barrier in coeliac disease: why the gut vascular barrier matters.

Gut·2026
Same author

Optimizing bowel preparation regimens for colon capsule endoscopy: an umbrella review (overview of systematic reviews).

Therapeutic advances in gastrointestinal endoscopy·2026
Same author

Enhancing the Evidence: Critical Insights and Future Directions for Texture and Color Enhancement Imaging in Colorectal Neoplasia Detection.

JGH open : an open access journal of gastroenterology and hepatology·2026
Same author

Patient-Level Predictors of Procedural Success in Colon Capsule Endoscopy: A Systematic Review and Meta-Analysis.

Journal of gastroenterology and hepatology·2026
Same author

Non-visualized Ultrasonography Should Remain Indeterminate in Patency Capsule Localization.

DEN open·2026

Related Experiment Video

Updated: May 7, 2026

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body
08:08

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body

Published on: January 11, 2018

7.2K

Capsule-odometer: a concept to improve accurate lesion localisation.

Alexandros Karargyris1, Anastasios Koulaouzidis

  • 1Alexandros Karargyris, National Library of Medicine, National Institutes of Health, Bethesda, MD 20814, United States.

World Journal of Gastroenterology
|October 15, 2013
PubMed
Summary

A novel capsule endoscopy design with wheels and a spring mechanism improves lesion localization and video stabilization in the small bowel. This innovation enhances diagnostic accuracy for gastrointestinal examinations.

Keywords:
Capsule endoscopyHardwareLocalisationOdometerSoftware

More Related Videos

Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly
12:50

Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly

Published on: April 14, 2014

41.0K
Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
10:10

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research

Published on: November 2, 2018

8.9K

Related Experiment Videos

Last Updated: May 7, 2026

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body
08:08

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body

Published on: January 11, 2018

7.2K
Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly
12:50

Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly

Published on: April 14, 2014

41.0K
Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
10:10

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research

Published on: November 2, 2018

8.9K

Area of Science:

  • Medical Devices
  • Gastroenterology
  • Biomedical Engineering

Background:

  • Small-bowel capsule endoscopy is crucial for diagnosing gastrointestinal conditions.
  • Accurate lesion localization remains a challenge in current capsule endoscopy.
  • Video stabilization is needed to overcome erratic movements within the digestive tract.

Purpose of the Study:

  • To introduce a modified capsule endoscopy design with enhanced localization and stabilization capabilities.
  • To develop a prototype using 3-D printing technology for improved small-bowel visualization.
  • To evaluate the feasibility of the new capsule design in preclinical settings.

Main Methods:

  • A modified capsule prototype was designed with protruding wheels and a spring mechanism.
  • Three-dimensional (3-D) printing technology was utilized for prototype fabrication.
  • In vitro and ex vivo experiments were conducted using porcine small-bowel models.

Main Results:

  • The modified capsule design theoretically offers odometer capabilities for precise lesion localization.
  • The integrated spring mechanism and wheels aim to stabilize video recordings by minimizing erratic movements.
  • Proof-of-concept experiments demonstrated the potential of the 3-D printed prototype.

Conclusions:

  • The proposed capsule endoscopy modification shows promise for improving diagnostic accuracy in small-bowel investigations.
  • Further research and in vivo experiments are warranted to validate the clinical utility of this enhanced capsule design.
  • This innovation has the potential to refine gastrointestinal imaging techniques and patient outcomes.