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Published on: June 25, 2019
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Speed of word retrieval in multiple sclerosis
Ahmad Reza Khatoonabadi1, Vahid Shaygan Nejad, Hooshang Dadgar
1Department of Speech-Therapy, Faculty of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran.
Summary
Multiple sclerosis (MS) patients exhibit delayed processing speed compared to healthy individuals. This cognitive impairment affects their ability to perform daily tasks, highlighting the need for targeted interventions.
Area of Science:
- Neuroscience
- Cognitive Psychology
Background:
- Multiple sclerosis (MS) is an inflammatory central nervous system disease affecting myelin.
- Cognitive deficits, including memory and processing disorders, are common in MS patients.
Purpose of the Study:
- To evaluate the processing speed in multiple sclerosis patients using a word-finding assessment.
- To compare processing speed between MS patients and healthy controls across different word categories.
Main Methods:
- A case-control study involving 47 MS patients and 29 healthy controls.
- Reaction time (RT) was measured using a word-finding task with familiar words (fruits, animals, objects).
- Data analyzed using repeated measure ANOVA, two-way ANOVA, and independent-samples t-test.
Main Results:
- MS patients demonstrated significantly slower processing speed compared to healthy controls.
- A significant difference in mean reaction time was observed across all three word categories (P < 0.001).
Conclusions:
- Processing speed is demonstrably impaired in individuals with multiple sclerosis.
- Further research and treatment strategies focusing on processing speed are crucial for managing memory-related daily activities in MS patients.

