[Relevance between carotid plaque scores and the severity of coronary atherosclerosis]
Insights
Carotid plaque assessment using ultrasonography can predict coronary artery disease severity. Higher plaque scores correlate with more severe coronary artery disease, aiding clinical prediction.
Area of Science:
- Cardiovascular Medicine
- Diagnostic Imaging
- Medical Research
Context:
- Coronary artery disease (CAD) is a leading cause of mortality worldwide.
- Assessing CAD severity is crucial for effective patient management.
- Non-invasive methods for predicting CAD severity are highly sought after.
Purpose:
- To investigate the correlation between carotid plaque characteristics and the extent of coronary artery disease.
- To determine if carotid ultrasonography can serve as a predictor for CAD severity.
Summary:
- This study analyzed 207 patients undergoing coronary angiography, categorizing them by CAD severity (1-vessel, 2-vessel, or 3-vessel disease).
- Carotid plaque presence was significantly higher in patients with two-vessel disease (2VD) and three-or-more-vessel disease (3VD) compared to one-vessel disease (1VD).
- Carotid plaque scores demonstrated a positive correlation with Gensini and Leaman scores, indicating greater CAD severity.
Impact:
- Carotid ultrasonography offers a clinically relevant, non-invasive tool for predicting coronary artery disease severity.
- This finding can potentially improve risk stratification and guide treatment decisions in patients with suspected CAD.
- Integrating carotid plaque assessment into routine practice may enhance early detection and management of cardiovascular disease.
Objective:
To explore the relevance between carotid plaque and the severity of coronary artery disease.
Methods:
A total of 207 patients(149 males,58 females) undergoing coronary angiography were definitely diagnosed with coronary heart disease. They were divided into 3 groups of one-vessel disease (1VD, n = 69), two-vessel disease (2VD, n = 57) and three-or-more vessel disease (3VD, n = 81) by the number of involved vessels. Their physical findings, biochemical data and carotid ultrasonographic results were collected. And the scores of Crouse, Gensini and Leaman were calculated to compare the relevance.
Results:
No significant differences existed among all three groups except for a higher age and the presence of plaque in 2VD and 3VD groups than 1VD group ((63 ± 11) and (60 ± 11) vs (57 ± 10)years old, 82%(n = 47) and 81%(n = 66) vs 65%(n = 45), both P < 0.05) . Crouse had a positive correlation with Gensini (r = 0.455, P < 0.01) and Leaman scores (r = 0.358, P < 0.01) .
Conclusion:
Assessment of plaque scores by carotid ultrasonography is clinically relevant for predicting the severity of coronary artery disease.
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