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[Epidemiological characteristics of hepatitis C in Henan province]
Pan-ying Fan1, Ding-yong Sun, Yan-min Ma
1Henan Provincial Centre for Disease Control and Prevention, Zhengzhou 450016, China.
Insights
Hepatitis C virus (HCV) infection remains low in Henan province overall, but specific regions show higher prevalence, necessitating continued monitoring and targeted prevention strategies for this infectious disease.
Area of Science:
- Epidemiology
- Hepatology
- Public Health
Context:
- Henan province implemented comprehensive Hepatitis C virus (HCV) control measures.
- Understanding the current epidemiological landscape of HCV is crucial for public health strategies.
Purpose:
- To determine the epidemiological characteristics of Hepatitis C virus (HCV) infection in the general population of Henan province.
- To assess the prevalence and distribution of HCV infection following control initiatives.
Summary:
- A 2012 study surveyed 32,203 individuals aged 1-75 in Henan province.
- Overall anti-HCV and HCV RNA prevalence rates were 0.64% and 0.35%, respectively, with higher rates in older age groups and urban areas.
- While overall prevalence is low, regional variations indicate persistent localized epidemics.
Impact:
- Provides baseline data on HCV prevalence in Henan province post-intervention.
- Highlights the need for geographically targeted public health interventions for Hepatitis C.
- Informs future HCV prevention and control strategies in China.
Objective:
To understand the epidemiological characteristics of hepatitis C in Henan province.
Methods:
Multistage sampling was used to investigate a group of 1-75 year-old general population, living in 30 districts of 18 cities, Henan province. Blood samples were collected and tested for anti-HCV and hepatitis C virus(HCV), from April to July 2012.
Results:
32 203 persons were investigated. Among the general population aged 1 to 75 years old, the overall prevalence rates of anti-HCV and HCV RNA were 0.64% and 0.35% respectively. The prevalence rates of anti-HCV among males and females were 0.60%, and 0.68% respectively, with the rates of HCV RNA as 0.37%, and 0.33% respectively. The prevalence rates of anti-HCV and HCV RNA were increasing with age. The prevalence rates of anti-HCV and HCV RNA in urban area were 0.58% and 0.32%, and in rural area as 0.41%, and 0.19% respectively.
Conclusion:
After the implementation of comprehensive measures for HCV control and prevention, Henan province became low prevalent for HCV infection. Our data revealed that the overall prevalence remained low, but the epidemic was severe in some geographical regions in Henan province.
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