Immunomodulators and allergy

The role played by immunomodulation in allergy is critically reviewed. The prospective mechanisms of immunomodulation, specifically including those showing relation with allergic phenomena, are taken into consideration, examining the main interfering factors. Type I, IgE-mediated immunoreaction, in its two aspects, IgE synthesis and mediator's release, is analyzed, bearing in mind some agents involved or affecting these processes, mimicking immunomodulation. Other agents, such as Corynebacterium granulosum derivatives and glucocorticoids have been also appraised, to highlight their action in this connection.