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Benign infantile convulsions associated with mild gastroenteritis: an electroclinical study of 34 patients

Tingsong Li1, Siqi Hong1, Xing Peng2

  • 1Department of Neurology, Children's Hospital of Chongqing Medical University, Chongqing, China.

Seizure
|October 16, 2013
PubMed

Insights

Convulsions with mild gastroenteritis (CwG) primarily affect toddlers. Phenobarbital effectively controls seizures during the acute phase, and long-term anticonvulsants are not needed for a good prognosis.

Area of Science:

  • Pediatric Neurology
  • Infectious Diseases

Background:

  • Convulsions with mild gastroenteritis (CwG) is a specific epilepsy syndrome.
  • Understanding its electroclinical features and evolution is crucial for effective management.

Purpose of the Study:

  • To analyze the electroclinical features and evolution of patients diagnosed with convulsions with mild gastroenteritis (CwG) in southwest China.

Main Methods:

  • Retrospective analysis of medical records for 34 patients diagnosed with CwG.
  • Follow-up duration of at least 12 months for all patients.

Main Results:

  • The age of onset ranged from 6 to 29 months, with a female/male ratio of 1.62.
  • Phenobarbital was highly effective (83.33%) in controlling seizures during the acute phase.
  • Most patients (33/34) exhibited normal psychomotor development and remained seizure-free during follow-up.

Conclusions:

  • CwG predominantly affects toddlers and is often associated with gastroenteritis.
  • Phenobarbital is the preferred first-line treatment for acute seizures in CwG.
  • Long-term anticonvulsant therapy is generally not required for a favorable prognosis in CwG patients.
Abstract

Keywords:
AEDsBenign convulsionsCSFCwGEEGElectroclinical featuresEnteroteritisILAEInternational League Against Epilepsyanti-epilepticus drugsbenign convulsions associated with mild gastroenteritiscerebrospinal fluidelectroencephalography

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