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Scaffold hopping approach towards various AFQ-056 analogs as potent metabotropic glutamate receptor 5 negative

Holger Kubas1, Udo Meyer, Mirko Hechenberger

  • 1Merz Pharmaceuticals GmbH, Eckenheimer Landstrasse 100, 60318 Frankfurt am Main, Germany.

Bioorganic & Medicinal Chemistry Letters
|October 16, 2013
PubMed

Keywords:
AFQ-056Allosteric modulatorCIZDIEPYKQXGQG-UHFFFAOYSA-NMetabotropic glutamate receptorOFNVYYXEOJUGRH-UHFFFAOYSA-NSONLNLJEFBMKGV-UHFFFAOYSA-NScaffold hoppingmGluR5

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