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Updated: May 7, 2026

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18F-FDG-PET/CT in a patient with suspected recurrence of germ cell tumor
Daniele Penna1, Vincenzo Arena, Ettore Pelosi
1PET/CT center, IRMET SpA Euromedic, Via Onorato Vigliani 89/A, 10138, Torino, Italy.
Abstract:
At present, the available clinical practice guidelines for the management of patients with germ cell tumor (GCT) assign to Positron Emission Tomography (PET) scan a role in the evaluation of the residual mass at the end of the treatment of advanced seminoma, while a possible role of this tool in the strategy of follow-up has not been defined yet. We are presenting a case of a patient treated for a GCT with an increase of the marker levels during the follow-up where a PET/CT with 18F-FDG was the only noninvasive examination able to correctly identify the site of disease recurrence. This case shows how this tool could have a role, in addition to morphological examinations, in the management of patients with GCT during the follow-up.
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