Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

57
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
57
Stroke: Introduction and Types01:29

Stroke: Introduction and Types

75
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
75
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

57
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
57
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

891
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
891
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

41
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
41
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

74
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
74

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is screening for domestic violence routinely performed during pregnancy? Insights from women delivering in a referral hospital in Northern Italy.

Minerva obstetrics and gynecology·2026
Same author

Markers in umbilical cord blood in early-onset fetal growth restricted fetuses.

Placenta·2026
Same author

Free pelvic fluid detection and quantification using transvaginal ultrasound: a surrogate marker for retrograde menstruation.

Reproductive biomedicine online·2026
Same author

Challenging the paradigm that neonatal uterine bleeding represents the first menstrual episode.

Scientific reports·2026
Same author

Endometriosis and ovarian cancer: epidemiological evidence, molecular insights, and clinical decision-making.

Human reproduction update·2026
Same author

Phenotyping Preeclampsia Using Unsupervised Machine Learning: A Prospective Cohort Study.

BJOG : an international journal of obstetrics and gynaecology·2026
Same journal

Management of hypertensive disorders in pregnancy.

Current opinion in obstetrics & gynecology·2026
Same journal

Updates in group prenatal care research.

Current opinion in obstetrics & gynecology·2026
Same journal

Complex benign gynecology in perimenopause: current evidence and future directions.

Current opinion in obstetrics & gynecology·2026
Same journal

Role of insulin in female reproduction.

Current opinion in obstetrics & gynecology·2026
Same journal

Urinary tract involvement in endometriosis: current evidence and clinical insights into navigating diagnosis and management.

Current opinion in obstetrics & gynecology·2026
Same journal

Updates in ultrasound imaging of adenomyosis and clinical impacts.

Current opinion in obstetrics & gynecology·2026
See all related articles

Related Experiment Video

Updated: May 7, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.4K

Stroke during pregnancy and pre-eclampsia.

Francesca Crovetto1, Edgardo Somigliana, Anna Peguero

  • 1aDepartment of Obstetrics and Gynecology, Fondazione Ca' Granda, Ospedale Maggiore Policlinico; UniversitĂ  degli Studi di Milano, Milan, Italy bDepartment of Maternal-Fetal Medicine, Institute ClĂ­nic of Gynecology, Obstetrics and Neonatology (ICGON), Hospital Clinic-IDIBAPS, University of Barcelona and Centre for Biomedical Research on Rare Diseases (CIBER-ER), Barcelona, Spain cInfertility Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Current Opinion in Obstetrics & Gynecology
|October 16, 2013
PubMed
Summary
This summary is machine-generated.

Stroke risk increases during pregnancy, especially postpartum. Pre-eclampsia/eclampsia significantly elevates this risk, necessitating prompt evaluation and management including blood pressure control and thromboprophylaxis for affected women.

More Related Videos

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

10.5K
Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

15.1K

Related Experiment Videos

Last Updated: May 7, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
05:31

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles

Published on: January 26, 2024

1.4K
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

10.5K
Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
12:02

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

Published on: July 30, 2016

15.1K

Area of Science:

  • Neurology
  • Obstetrics
  • Cardiovascular Medicine

Background:

  • Stroke incidence rises during pregnancy and the postpartum period.
  • Pre-eclampsia and eclampsia are significant risk factors for stroke in this population.

Purpose of the Study:

  • To review the association between stroke and pre-eclampsia/eclampsia.
  • To summarize diagnostic approaches for stroke in these patients.
  • To outline management strategies for stroke in pre-eclampsia/eclampsia.

Main Methods:

  • Literature review of existing data on stroke in pre-eclampsia/eclampsia.
  • Analysis of diagnostic criteria and neuroimaging techniques.
  • Evaluation of preventive and therapeutic interventions.

Main Results:

  • Pre-eclampsia/eclampsia is diagnosed in approximately one-third of pregnancy-related strokes.
  • Hemorrhagic stroke is more prevalent than ischemic stroke, likely due to severe hypertension.
  • Severe headache is the most frequent presenting symptom, necessitating neuroimaging.

Conclusions:

  • Stroke risk must be considered in women with pre-eclampsia or eclampsia.
  • Prompt neurological evaluation is crucial for symptomatic patients.
  • Blood pressure management and thromboprophylaxis are key preventive measures.