[Value of Soludactone in cardiac surgery in adults]

The use of potassium canrenoate (Soludactone) in the post-operative period in 31 patients who had undergone open-heart surgery, in comparison with a control batch of patients, led to a more rapid and easier regression of myocardial hyperexcitability, the maintenance of kaliemia at values near normal, a reduction in kaliuresis, a rapid elevation of the urinary Na/K ratio and the maintenance of satisfactory diuresis. But the majority of these effects appear progressively during the first 3 days of treatment, so potassium canrenoate should be prescribed 3 days before the intervention so that the beneficial effects may be manifested from the day of the intervention itself.