Relation between inhibition of calmodulin and mediator release from rat mast cells
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General Pharmacology
|January 1, 1985
Abstract:
Cationic drugs that interact with calmodulin such as chlorpromazine, trifluoperazine, W-7 and lidocaine caused dose-dependent release of mediator from rat mast cells. A significant correlation was observed between the effects of test drugs with different structure in causing mediator release and calmodulin inhibition.