Abnormal signal intensities of the seminal vesicles in a screening population

To investigate the incidence of abnormal signal hyperintensity on T1-weighted magnetic resonance imaging (MRI) of the seminal vesicles in a screening population in order to compare clinical indicators between subjects with and without signal abnormality.

Signal intensity of the seminal vesicles on T1-weighted images and clinical examinations were investigated in 3570 examinations of 1865 male subjects (mean age 54.8 years, range 23-86 years at the first examination).

Abnormal signal hyperintensity was observed at least once in 32 subjects (1.7%). Subjects with the abnormality were significantly older (average age with and without the abnormality, 64.1 vs. 54.6, respectively, P < 0.001), and the incidence of abnormality increased with increasing age (0% for the age group <40, 0.3% for 40-49, 1.3% for 50-59, 2.9% for 60-69, 5.9% for 70-79, and 10.1% for >80). No significant difference was found in clinical indicators except for serum creatinine (1.10 vs. 0.84 mg/dL, P < 0.001). Of 12 subjects with abnormal signal intensity and follow-up data, the finding persisted on the same side for at least 11 months in seven subjects (58%).

Abnormal signal intensity of the seminal vesicles was observed in 1.7% of screening population, and the imaging finding in isolation is unlikely to have clinical significance.