Current status of patients with buerger disease in Japan

Noriyuki Hida1, Takashi Ohta

  • 1Department of Vascular Surgery, Aichi Medical University, Nagakute, Aichi, Japan.

Insights

This study analyzed Japanese patients with Buerger disease (thromboangiitis obliterans). The findings indicate a favorable clinical course for thromboangiitis obliterans patients in Japan, with manageable limb morbidity and mortality rates.

Area of Science:

  • Vascular Medicine
  • Epidemiology

Background:

  • Buerger disease, also known as thromboangiitis obliterans (TAO), is a rare inflammatory condition affecting blood vessels, primarily in the limbs.
  • Understanding the prevalence and clinical characteristics of TAO is crucial for effective patient management and public health planning in Japan.

Purpose of the Study:

  • To analyze the prevalence and clinical characteristics of Japanese patients diagnosed with thromboangiitis obliterans (TAO).
  • To estimate the current number of TAO patients in Japan and assess their clinical outcomes.

Main Methods:

  • Utilized the Ministry of Health, Labour and Welfare (MHLW) database from 2009.
  • Included 129 newly diagnosed patients and 3639 patients undergoing follow-up, adhering to established clinical criteria for TAO.

Main Results:

  • Estimated the total number of patients with thromboangiitis obliterans (TAO) in Japan to be approximately 4000.
  • Observed a relatively favorable clinical course for TAO patients.
  • Reported that rates of limb morbidity and mortality were not entirely discouraging.

Conclusions:

  • The study provides valuable epidemiological data on thromboangiitis obliterans (TAO) in Japan.
  • The findings suggest that TAO management in Japan may lead to relatively positive patient outcomes.
  • Further research can build upon these findings to improve care for patients with Buerger disease.