Related Experiment Video
Updated: May 6, 2026

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
Managing opioid dependence in pregnancy -- a general practice perspective
Shalini Arunogiri1, Lea Foo, Matthew Frei
1MBBS, MPsych, FRANZCP, is an Addiction Psychiatry Registrar, Turning Point Alcohol and Drug Centre, Eastern Health, Melbourne, Victoria.
Background:
Managing opioid dependence in pregnant women is a complex and potentially challenging task. Drug-dependent women may be difficult to engage in antenatal care and opioid substitution requires careful dose titration. Pregnancy, however, can be an opportune time to effect behaviour change, and supporting an opioid-dependent woman through pregnancy can be a rewarding clinical experience.
Objective:
This article provides an overview of treatment principles for managing opioid dependence in pregnancy, and reviews current treatment guidelines for use of opioid-substitution therapy in pregnant women.
Discussion:
The management of opioid dependence during pregnancy requires holistic and comprehensive assessment and referral to specialist services is often appropriate. Specific issues that may need to be addressed include decision-making regarding the choice of opioid-substitution therapy and the potential for neonatal abstinence syndrome in the newborn. General practitioners are often well placed to support and coordinate care of their opioid-dependent pregnant patients.
Related Concept Videos
Analgesia and Pain Management
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Opioid Analgesics: Morphine and Other Natural Cogeners
Drug Dependence
Drug Abuse and Addiction: Pharmacological Phenomena
Pharmaceutical Poisoning: Treatment Strategies

