Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

61
Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal...
61
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

1.5K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.5K
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

79
Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows...
79
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

95
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
95
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

64
Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
64
Drugs for Treatment of Ulcerative Colitis in IBD01:29

Drugs for Treatment of Ulcerative Colitis in IBD

721
Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
721

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterisation of Allergen Profiles in Commercial Egg Products to Inform Oral Immunotherapy Strategies in Egg Allergy.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026
Same author

IS THERE A RELATIONSHIP BETWEEN INTESTINAL FRUCTOSE MALABSORPTION, GASTROINTESTINAL SYMPTOMS AFTER FRUCTOSE OVERLOAD, AND BODY ADIPOSITY IN ADOLESCENTS?

Arquivos de gastroenterologia·2026
Same author

Correlation and Agreement Between Parent-Report and Self-Report Food Allergy Quality of Life Questionnaires After Oral Immunotherapy.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026
Same author

Prevention of pediatric functional constipation: a narrative review.

Jornal de pediatria·2026
Same author

Probiotic oral immunotherapy for egg and milk allergy induces sustained unresponsiveness.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2025
Same author

Impact of Participant Baseline Factors on Exposure-Adjusted Incidence of Treatment-Related Adverse Events During Peanut Oral Immunotherapy.

The journal of allergy and clinical immunology. In practice·2025

Related Experiment Video

Updated: May 6, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
03:23

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

1.6K

Eosinophilic colitis in infants.

Adriana Chebar Lozinsky1, Mauro Batista de Morais1

  • 1Department of Pediatrics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Jornal De Pediatria
|October 18, 2013
PubMed
Summary
This summary is machine-generated.

Eosinophilic colitis, primarily affecting male infants under six months, is often caused by cow's milk allergy. Dietary exclusion of cow's milk protein is an effective treatment for this condition.

Keywords:
Alergia a leiteColiteColitisEosinophilsEosinófilosInfantLactenteMilk hypersensitivity

More Related Videos

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
05:39

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis

Published on: November 30, 2021

3.5K
Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
08:32

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

1.8K

Related Experiment Videos

Last Updated: May 6, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
03:23

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

1.6K
A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
05:39

A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis

Published on: November 30, 2021

3.5K
Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
08:32

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

1.8K

Area of Science:

  • Pediatric Gastroenterology
  • Allergy and Immunology

Background:

  • Eosinophilic colitis is a rare gastrointestinal disorder characterized by eosinophilic infiltration of the colon.
  • It predominantly affects infants and is often associated with food allergies.

Purpose of the Study:

  • To conduct a literature review of clinical data concerning infants diagnosed with allergic or eosinophilic colitis.
  • To identify the characteristics, causes, and effective management strategies for eosinophilic colitis in infants.

Main Methods:

  • A comprehensive MEDLINE search was performed using keywords related to allergic and eosinophilic colitis.
  • Articles published between 1966 and February 2013 describing patient characteristics were selected for review.

Main Results:

  • The review included 32 articles detailing 314 infants, with 61.6% being male and 78.6% under six months old.
  • Cow's milk protein was identified as a common trigger (44.2% of cases), with eosinophilia confirmed in 43.8% of infants.
  • Dietary elimination of cow's milk protein led to improvement in most patients.

Conclusions:

  • Eosinophilic colitis is most common in males within the first six months of life.
  • Cow's milk allergy is considered the primary etiology.
  • Excluding cow's milk from the infant's or lactating mother's diet is a generally effective therapeutic approach.