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Factors affecting particle collection by electro-osmosis in microfluidic systems
Mohd Nazim Mohtar1, Kai F Hoettges, Michael P Hughes
1Centre for Biomedical Engineering, Department of Mechanical Engineering Sciences, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey, UK; Department of Electrical and Electronic Engineering, Faculty of Engineering, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Electrophoresis
|October 18, 2013
Summary
Alternating-current electro-osmosis effectively concentrates particles using fluid vortices and sedimentation. Viscosity significantly impacts particle trapping, with vortex height determining collection limits.
Area of Science:
- Physics
- Fluid Dynamics
- Electrokinetics
Background:
- Alternating-current electro-osmosis (ACEO) induces fluid transport and particle concentration.
- ACEO offers advantages over other particle trapping methods, including scalable trapping and defined vortex heights.
Purpose of the Study:
- To investigate particle collection using ACEO across various conditions.
- To model the collection behavior governed by vortex dynamics and sedimentation.
Main Methods:
- Examined particle collection with varying particle concentrations, electrode gaps, chamber heights, and media viscosity/density.
- Developed a model describing collection driven by vortices and sedimentation.
Main Results:
- Particle collection is governed by vortex-driven and sedimentation processes.
- Maximum vortex-driven collection height was determined.
- High particle concentrations and fluid velocities limit trapping effectiveness.
- Media viscosity is a more significant factor than density in particle trapping.
Conclusions:
- ACEO is an effective method for particle concentration, with collection influenced by fluid dynamics and particle properties.
- The study provides a model for predicting ACEO collection behavior and identifies key parameters like viscosity.
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