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Improvement of left ventricular diastolic function and left atrial reverse remodeling after catheter ablation of

Mehmet Akkaya1, Henri Roukoz, Selcuk Adabag

  • 1Cardiovascular Division, University of Minnesota Medical School, Minneapolis, MN, USA.

Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing
|October 18, 2013
PubMed

Insights

Catheter ablation for premature ventricular complexes (PVCs) significantly improved left ventricular diastolic function and reduced left atrial size. This procedure offers benefits beyond systolic performance, impacting overall cardiac remodeling.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Imaging

Background:

  • Catheter ablation of premature ventricular complexes (PVCs) is known to improve left ventricular (LV) systolic performance.
  • The impact of PVC ablation on LV diastolic function and left atrial (LA) remodeling remains less understood.
  • Assessing these diastolic and remodeling parameters is crucial for a comprehensive understanding of ablation outcomes.

Purpose of the Study:

  • To evaluate the effects of catheter ablation for symptomatic PVCs on LV diastolic function.
  • To assess the impact of PVC ablation on left atrial (LA) remodeling.
  • To determine if PVC ablation leads to reverse remodeling of the left atrium.

Main Methods:

  • Prospective evaluation of 47 patients undergoing PVC ablation using two-dimensional echocardiography.
  • Diastolic function assessed via mitral inflow parameters (E, A, E/A, DT) and mitral annular velocity (Ea).
  • Left atrial volume index (LAVI) measured using modified biplane Simpson's method pre- and post-ablation.

Main Results:

  • Significant improvements observed in LV diastolic function, including increased E/A ratio and Ea, and decreased E/Ea ratio post-ablation.
  • Left atrial volume index (LAVI) significantly decreased after PVC ablation, indicating reverse remodeling.
  • Improvements in diastolic parameters and LAVI were noted even in patients with normal baseline LV ejection fraction.

Conclusions:

  • Catheter ablation of PVCs effectively improves left ventricular diastolic function.
  • The procedure promotes significant left atrial reverse remodeling.
  • These findings highlight the broader benefits of PVC ablation on cardiac structure and function.
Abstract

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