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Related Experiment Video

Updated: May 6, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
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Penile metastasis from primary bladder tumour.

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  • 1Urology Departmentand.Hospital Clinico Universitario. Valladolid.Spain.

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|October 19, 2013
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Summary

This case report details a rare instance of penile metastasis originating from bladder cancer. Diagnosis required histopathological examination of the skin lesion to confirm its urothelial carcinoma origin.

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Area of Science:

  • Urology
  • Oncology
  • Dermatology

Background:

  • Bladder cancer, specifically high-grade urothelial carcinoma, can present with rare metastatic patterns.
  • Penile metastasis is an uncommon manifestation of advanced malignancy.

Observation:

  • A 68-year-old male with advanced bladder cancer (T3N2M0) developed a painless, ulcerated lesion on the glans penis.
  • Initial presentation mimicked other dermatological conditions, necessitating further investigation.

Findings:

  • Histopathological analysis confirmed the penile lesion as a cutaneous metastasis of high-grade urothelial carcinoma.
  • This finding highlights the potential for diverse metastatic spread from primary bladder tumors.

Implications:

  • Early recognition and biopsy are crucial for diagnosing heterogeneous presentations of penile metastasis.
  • Understanding rare metastatic sites aids in comprehensive cancer staging and patient management.