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Updated: May 6, 2026

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
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A modified glaucoma staging system based on visual field index
Kazunori Hirasawa1, Nobuyuki Shoji, Tetsuya Morita
1Department of Ophthalmology, Graduate School of Medical Science, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan, hirasawa@kitasato-u.ac.jp.
Summary
A new modified glaucoma staging system (Modified GSS) using visual field index (VFI) is accurate and easy to use. Its performance is comparable or superior to existing glaucoma staging systems.
Area of Science:
- Ophthalmology
- Visual Science
Background:
- Glaucoma staging systems are crucial for patient management.
- Existing systems may have limitations in accuracy and ease of use.
Purpose of the Study:
- To introduce a modified glaucoma staging system (Modified GSS) utilizing the visual field index (VFI).
- To evaluate the performance of the Modified GSS against the Bascom Palmer GSS and Enhanced GSS.
Main Methods:
- Retrospective analysis of 549 eyes.
- Classification of glaucomatous visual field defects into stages 0-5 using VFI.
- Derivation of VFI cutoff values via receiver operating characteristic analysis.
- Comparison of staging performance with Advanced Glaucoma Intervention Study (AGIS) and Collaborative Initial Glaucoma Treatment Study (CIGTS) scores.
Main Results:
- VFI cutoff values for stages were determined as 81.5, 62.5, 42.5, and 22.5%.
- Modified GSS showed a stronger correlation than Bascom Palmer GSS (p < 0.001).
- Modified GSS and Enhanced GSS demonstrated equivalent correlation coefficients.
- Enhanced GSS tended to overstage moderate to severe AGIS and CIGTS scores (p < 0.001).
Conclusions:
- The Modified GSS offers a user-friendly and accurate method for glaucoma staging.
- Its performance is on par with or better than current glaucoma staging systems.
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