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Tear-Derived Exosomal miR-15a as New Diagnostic Tool for Diabetic Retinopathy
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[Regarding the method of the total tear production assessment]
Vestnik Oftalmologii
|October 22, 2013
Abstract:
Different Schirmer test I techniques presented in the literature have been reviewed and a comparative study of Schirmer test I results obtained with the eyes opened and closed has been conducted. The total tear production with the eyes opened vs. closed averaged 17.1+/-1.1 mm and 12-1.2 correspondingly (p=0.001; Mann-Whitney U test). In 22% of patients values were higher with the eyes closed rather than opened. The authors recommend to specify the conditions of the performed test when entering the results into the patient's chart.
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