Related Experiment Video
Updated: May 6, 2026
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Comparison between Gleason score and apparent diffusion coefficient obtained from diffusion-weighted imaging of
Rocchina Caivano1, Paola Rabasco, Antonella Lotumolo
1I.R.C.C.S.-C.R.O.B. Rionero in Vulture (Pz), Italy,1.
Objectives:
To correlate the apparent diffusion coefficient (ADC) of prostate cancer patients with pathological Gleason scores (GS).
Methods:
40 patients with GS 2 + 3, 3 + 3, 3 + 4, or 4 + 4 were selected. The magnetic resonance imaging (MRI) study was performed adding axial diffusion-weighted imaging (DWI) sequences to the standard MRI protocol. ADC values obtained were correlated with the GS data.
Results:
Statistically significant differences of ADC (p < .05) were found among GS groups with a trend of decreasing ADC values with increasing GS.
Conclusions:
The ADC values may help clinicians to delineate prostate carcinoma, recognizing its high- or low-grade compartments.
