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The tryptophans of gramicidin are essential for the lipid structure modulating effect of the peptide
Biochimica Et Biophysica Acta
|October 24, 1985
Abstract:
It is shown that N-formylation of the tryptophan residues of gramicidin completely and reversibly blocks the hexagonal HII phase-inducing ability of the peptide in dioleoylphosphatidylcholine model membranes.
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