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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Drug Toxicity: Allergic Reactions01:30

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Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
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Tertiary Healthcare System01:21

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Specialized care provided over an extended period is called tertiary care. Usually, a primary or secondary care physician will refer a patient to tertiary care. A patient's maximum physical and mental function is restored in tertiary care, which is caused due to the impact of a chronic illness or condition. Tertiary care aims to achieve the highest level of functioning possible while managing chronic illness. For example, a patient who falls and fractures their hip will need secondary care...
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Contact dermatitis mimickers: a tertiary care center's experience.

Yuliya Velykoredko, Marie-Claude Houle, Sandy Skotnicki

    Journal of Cutaneous Medicine and Surgery
    |October 22, 2013
    PubMed
    Summary

    Contact dermatitis (CD) can resemble other skin conditions. Recognizing these mimickers is crucial for timely diagnosis and proper treatment of patients.

    Area of Science:

    • Dermatology
    • Allergy and Immunology

    Background:

    • Contact dermatitis (CD) is a prevalent skin condition with diverse clinical presentations.
    • Numerous dermatologic conditions can mimic CD, necessitating a broad differential diagnosis.

    Observation:

    • A retrospective analysis identified patients misdiagnosed with CD.
    • Conditions like 2 feet-1 hand syndrome, Dermatitis Herpetiformis, Sézary syndrome, and Pityriasis Rubra Pilaris were misdiagnosed as CD.

    Findings:

    • Misdiagnosis of CD mimickers leads to significant diagnostic delays.
    • Delayed diagnosis hinders the timely initiation of appropriate patient interventions.

    Implications:

    • Considering differential diagnoses is essential for accurate CD diagnosis.

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  • Prompt recognition of CD mimickers ensures optimal patient outcomes and treatment pathways.