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Rhythm outcome predictors after concomitant surgical ablation for atrial fibrillation: a 9-year, single-center
Simon Pecha1, Timm Schäfer1, Irina Subbotina1
1Department of Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany.
Insights
Surgical ablation for atrial fibrillation (AF) is safe. Predictors for successful rhythm outcome include immediate postoperative sinus rhythm, smaller left atrial diameter, shorter AF duration, and biatrial ablation for persistent AF.
Area of Science:
- Cardiology
- Cardiac Surgery
- Electrophysiology
Background:
- Concomitant surgical ablation is guideline-recommended for patients with atrial fibrillation (AF) undergoing cardiac surgery.
- Identifying predictors of rhythm outcome is crucial for optimizing patient selection and procedural success.
Purpose of the Study:
- To identify predictors of sinus rhythm (SR) outcome 1 year after concomitant surgical AF ablation.
- To analyze the safety and feasibility of surgical AF ablation in a single center.
Main Methods:
- A single-center analysis of 503 patients with persistent or paroxysmal AF undergoing surgical ablation between January 2003 and January 2012.
- Ablation lesion sets included pulmonary vein isolation, left atrial lesions, or biatrial lesions.
- Rhythm evaluations were performed using Holter ECGs and event recorders at 3, 6, and 12 months postoperatively.
Main Results:
- Overall, 59.9% of patients achieved SR at 1-year follow-up.
- Paroxysmal AF patients had significantly better SR outcomes than persistent AF patients (67.3% vs 54.8%, P=.0053).
- Significant predictors for SR included immediate postoperative SR (P<.001), left atrial diameter (P=.0019), AF duration (P=.018), and preoperative paroxysmal AF.
Conclusions:
- Immediate postoperative SR, smaller left atrial diameter, shorter AF duration, and preoperative paroxysmal AF are key predictors of successful rhythm control after 1 year.
- Biatrial ablation demonstrated significantly higher rates of conversion to SR compared to solitary left atrial ablation in persistent AF patients (64.9% vs 51.4%, P=.044).
- Concomitant surgical AF ablation is a safe and feasible procedure with favorable rhythm outcomes in selected patients.
Objectives:
Concomitant surgical ablation is a safe and feasible procedure, recommended by the guidelines for patients with atrial fibrillation (AF) undergoing cardiac surgery. We performed a single-center data analysis to identify the predictors of rhythm outcome in such patients.
Methods:
From January 2003 to January 2012, 503 patients with persistent (n = 296, 58.8%) or paroxysmal (n = 207, 41.2%) AF underwent concomitant surgical AF ablation. The lesions were limited to a pulmonary vein isolation (n = 76, 15.1%), a more complex left atrial lesion set (n = 353, 70.2%), or biatrial lesions (n = 74, 14.7%). Follow-up rhythm evaluations were based on either 24-hour Holter electrocardiograms or event recorder interrogation at 3, 6, and 12 months postoperatively. A sinus rhythm (SR) immediately postoperatively was defined as the first documented rhythm after weaning from extracorporeal circulation.
Results:
The mean patient age was 68.0 ± 9.5 years, and 336 (66.8%) were men. No major ablation-related complications occurred. After 1 year of follow-up, 59.9% of all patients were in SR, with significantly better results in patients with paroxysmal AF than in those with persistent AF (67.3% vs 54.8%, P = .0053). Additional statistically significant factors influencing SR after 1 year were left atrial diameter (P = .0019), AF duration (P = .018), and immediate postoperative SR (P < .001). Regarding only patients with persistent or longstanding-persistent AF, those with biatrial lesions had significantly greater rates of conversion to SR than those with solitary left atrial ablation (SR, 64.9% vs 51.4%; P = .044) after 12 months.
Conclusions:
The statistically significant predictors for SR after 1 year were left atrial diameter, AF duration, preoperative paroxysmal AF, immediate postoperative SR, and biatrial ablation for persistent AF.
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