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Updated: May 6, 2026

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Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells

Young-Sun Lee1, Hee-Sook Jun

  • 1Lee Gil Ya Cancer and Diabetes Institute, Gachon University, 7-45 Songdo-dong, Yeonsu-ku, Incheon 406-840, South Korea.

Metabolism: Clinical and Experimental
|October 22, 2013
PubMed

Keywords:
5′ AMP-activated protein kinaseAMPKAnti-apoptosisB-cell lymphoma-2B-cell lymphoma-extra largeB-cell translocation gene 2BTG2BadBcl-2Bcl-xlBcl-xl/Bcl2-associated death promoter homologBiPC/EBPCCAAT/enhancer-binding proteinCOUP-TFIICREBDPP-IVEGFRERERKEpacFoxG-protein coupled receptorGIPGLPGLP-1 receptorGLP-1RGLUTGPRGRPPHNFIPIRSIncretin hormoneMAPKMEKMPGFNFATNODPAKPCPCNAPIPKPancreatic isletPdx-1ProliferationSADSOXSREBPSry-related high mobility group boxTCF7L2TGFTXNIPType 2 diabetesbinding immunoglobulin proteincAMP response-binding proteinchicken ovalbumin upstream promoter transcription factor IIdipeptidyl peptidase IVendoplasmic reticulumepidermal growth factor receptorexchange protein activated by cAMPextracellular signal regulated kinaseforkhead boxglicentin-related polypeptideglucagon-like peptideglucose transporterglucose-dependent insulinotropic peptidehepatocyte nuclear factorinsulin receptor substrateintervening peptidemTORmajor proglucagon fragmentmammalian target of rapamycinmitogen-activated protein kinasemitogen-activated protein kinase kinasenonobese diabeticnuclear factor of activated T-cellsp21-activated kinasep90 ribosomal S6 kinasep90RSKpancreas duodenum homeobox 1phosphatidylinositolprohormone convertaseproliferating cell nuclear antigenprotein kinasesterol regulatory element binding proteinsynapses of amphids defectivethioredoxin-interacting proteintranscription factor 7-like 2 (T-cell specific, HMG-box)transforming growth factor

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