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Updated: May 6, 2026

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni
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Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni

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Mansonic neuroschistosomiasis

Otávio Augusto Moreno de Carvalho

    Arquivos De Neuro-Psiquiatria
    |October 22, 2013
    PubMed

    Insights

    Mansonic neuroschistosomiasis (MN), a severe complication of Schistosoma mansoni infection, frequently affects the spinal cord. Prompt diagnosis and treatment with corticosteroids and antiparasitic drugs are crucial for better outcomes.

    Area of Science:

    • Neurology
    • Infectious Diseases
    • Parasitology

    Background:

    • Mansonic neuroschistosomiasis (MN) is the most common and severe ectopic manifestation of Schistosoma mansoni infection.
    • Both the brain and spinal cord can be affected, with spinal cord involvement being more frequent.

    Purpose of the Study:

    • To describe the clinical presentation, diagnosis, and treatment of Mansonic neuroschistosomiasis.
    • To highlight the importance of early intervention in managing this parasitic neurological disease.

    Main Methods:

    • Review of clinical cases and diagnostic findings.
    • Analysis of treatment strategies including corticosteroids and antiparasitic drugs.

    Main Results:

    • Spinal cord MN is more frequently symptomatic than brain MN.
    • Symptom severity correlates with egg burden and inflammatory response.
    • Cerebrospinal fluid examination and MRI are key diagnostic tools.

    Conclusions:

    • Early diagnosis and prompt treatment are essential for favorable outcomes in Mansonic neuroschistosomiasis.
    • Combined therapy with corticosteroids and antiparasitic agents is the standard treatment approach.

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